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M D Smith Selected Research

Rheumatoid Arthritis

2/2015Quantifying not only bone loss, but also soft tissue swelling, in a murine inflammatory arthritis model using micro-computed tomography.
7/2008Modulation of CCR2 in rheumatoid arthritis: a double-blind, randomized, placebo-controlled clinical trial.
8/2007Characterisation of a dendritic cell subset in synovial tissue which strongly expresses Jak/STAT transcription factors from patients with rheumatoid arthritis.
12/2006Changes in synovial tissue Jak-STAT expression in rheumatoid arthritis in response to successful DMARD treatment.
1/2006Standardisation of synovial tissue infiltrate analysis: how far have we come? How much further do we need to go?
9/2004Escalated conventional therapy for rheumatoid arthritis patients.
5/2004T cells, fibroblast-like synoviocytes, and granzyme B+ cytotoxic cells are associated with joint damage in patients with recent onset rheumatoid arthritis.
7/2003Analysis of the cell infiltrate and expression of proinflammatory cytokines and matrix metalloproteinases in arthroscopic synovial biopsies: comparison with synovial samples from patients with end stage, destructive rheumatoid arthritis.
1/2003Osteoprotegerin expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathies and osteoarthritis and normal controls.
1/2003Etanercept treatment of rheumatoid arthritis in the "real world".
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M D Smith Research Topics

Disease

19Rheumatoid Arthritis
02/2015 - 10/2000
7Necrosis
09/2008 - 09/2001
6Arthritis (Polyarthritis)
02/2015 - 03/2001
5Osteoarthritis
06/2011 - 02/2001
5Erectile Dysfunction
11/2001 - 06/2000
4Infections
02/2014 - 05/2000
4Pain (Aches)
02/2014 - 02/2002
3Inflammation (Inflammations)
05/2011 - 01/2000
3Spondylarthropathies
09/2008 - 12/2002
3Melioidosis
08/2000 - 02/2000
2COVID-19
12/2020 - 07/2020
2Neoplasms (Cancer)
05/2013 - 05/2011
2Wounds and Injuries (Trauma)
01/2008 - 02/2000
2Chronic Obstructive Pulmonary Disease (COPD)
03/2001 - 08/2000
2Renal Insufficiency (Renal Failure)
08/2000 - 05/2000
2Sepsis (Septicemia)
03/2000 - 02/2000
1Gastroesophageal Reflux (GERD)
10/2018
1Deglutition Disorders (Dysphagia)
10/2018
1Chronic Disease (Chronic Diseases)
03/2015
1Breast Neoplasms (Breast Cancer)
05/2013
1Infertility (Sterility)
08/2011
1Pulmonary Arterial Hypertension
05/2011
1Pulmonary Fibrosis (Fibrosing Alveolitis)
05/2011
1Fibrosis (Cirrhosis)
05/2011
1Liver Failure
09/2009
1Acute Liver Failure (Fulminant Hepatic Failure)
09/2009
1Synovitis
09/2008
1Pneumococcal Infections
08/2008
1Neoplasm Metastasis (Metastasis)
06/2008
1Colorectal Neoplasms (Colorectal Cancer)
06/2008
1Hand Deformities (Hand Deformity)
03/2006
1Ankylosing Spondylitis
02/2006
1Telangiectasis (Telangiectasia)
01/2005
1Shoulder Pain
09/2004
1Osteolysis
02/2004
1Knee Osteoarthritis
12/2003

Drug/Important Bio-Agent (IBA)

7CytokinesIBA
02/2014 - 02/2000
7Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2003 - 02/2000
5Pharmaceutical PreparationsIBA
12/2020 - 03/2001
5Sildenafil Citrate (Viagra)FDA Link
11/2001 - 06/2000
4Interleukin-1beta (Interleukin 1 beta)IBA
09/2008 - 09/2001
4Antirheumatic Agents (DMARD)IBA
12/2006 - 04/2001
3Cell Adhesion MoleculesIBA
09/2008 - 09/2001
3LigandsIBA
07/2008 - 12/2002
3Adrenal Cortex Hormones (Corticosteroids)IBA
12/2003 - 01/2001
3Matrix Metalloproteinases (MMPs)IBA
07/2003 - 10/2000
2Anti-Bacterial Agents (Antibiotics)IBA
02/2014 - 02/2000
2AntibodiesIBA
05/2011 - 05/2011
2Proteins (Proteins, Gene)FDA Link
05/2011 - 02/2006
2Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
09/2008 - 09/2001
2Infliximab (Remicade)FDA Link
09/2008 - 02/2006
2Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
07/2008 - 02/2001
2ChemokinesIBA
01/2006 - 02/2001
2OsteoprotegerinIBA
02/2004 - 01/2003
2SteroidsIBA
12/2003 - 03/2001
2InterleukinsIBA
07/2003 - 02/2000
2Tissue Inhibitor of Metalloproteinase-1IBA
07/2003 - 10/2000
2Interleukin-6 (Interleukin 6)IBA
07/2003 - 02/2000
2Interleukin-10 (Interleukin 10)IBA
09/2001 - 02/2000
2MethylprednisoloneFDA LinkGeneric
11/2000 - 10/2000
2CreatinineIBA
08/2000 - 05/2000
2beta Lactam AntibioticsIBA
08/2000 - 05/2000
2Ceftazidime (Fortum)FDA LinkGeneric
08/2000 - 05/2000
1Proton Pump InhibitorsIBA
10/2018
1CollagenIBA
02/2015
1Prednisolone (Predate)FDA LinkGeneric
02/2015
1CyclinsIBA
05/2013
1Phenobarbital (Luminal)FDA Link
05/2013
1Nerve Growth Factor (NGF)IBA
06/2011
1tanezumabIBA
06/2011
1Immunoglobulin M (IgM)IBA
05/2011
1Rheumatoid FactorIBA
05/2011
1AutoantibodiesIBA
05/2011
1alpha-Fetoproteins (alpha-Fetoprotein)IBA
09/2009
1BilirubinIBA
09/2009
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
09/2009
1Alanine Transaminase (SGPT)IBA
09/2009
1Indicators and Reagents (Reagents)IBA
09/2009
1Conjugate VaccinesIBA
08/2008
1VaccinesIBA
08/2008
1Polysaccharides (Glycans)IBA
08/2008
1STAT Transcription FactorsIBA
08/2007
1Janus KinasesIBA
12/2006
11- hydroxy- 5,8- bis(2- ((2- hydroxyethyl)amino)ethylamino)- 9,10- anthracenedioneIBA
03/2006
1CoagulaseIBA
03/2006
1Carbon MonoxideIBA
01/2005
1Granzymes (Granzyme)IBA
05/2004

Therapy/Procedure

5Therapeutics
06/2011 - 10/2000
2Intravenous Infusions
08/2000 - 05/2000
1Fundoplication
10/2018
1Pain Management
03/2015
1Replacement Arthroplasty
02/2014
1Length of Stay
02/2014
1Fracture Fixation
02/2014
1Fluid Therapy (Oral Rehydration Therapy)
08/2011
1Injections
06/2011
1Hepatectomy
06/2008
1Pancreatectomy
01/2008
1Pancreaticoduodenectomy
01/2008
1Nerve Block (Nerve Blocks)
09/2004